Cannaregio is the northernmost sestiere of Venice and the first neighborhood most visitors encounter when arriving by train at Stazione di Santa Lucia. The broad Strada Nova, a 19th-century thoroughfare sliced through the medieval fabric, connects the station to the Rialto area and carries a steady stream of pedestrians past shops, gelaterias, and churches. Step off this main axis, though, and Cannaregio reveals a quieter, deeply residential character. The long, straight fondamente along its northern canals catch afternoon light and offer some of the most atmospheric walks in the city. Cannaregio is home to the Ghetto, the small island district where Venice's Jewish community was confined starting in 1516, giving the world the very word "ghetto." The area remains a center of Jewish life and memory, with its synagogues, the Jewish Museum, and a memorial to Holocaust victims. Other landmarks include the Gothic church of Madonna dell'Orto, once the parish church of painter Tintoretto (whose tomb lies inside), and the Ca' d'Oro, a jewel of Venetian Gothic architecture on the Grand Canal. With its mix of everyday Venetian routines and significant cultural sites, Cannaregio offers a rewarding balance between sightseeing and genuine neighborhood life.